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Bladder Cancer Nomogram
Bladder Cancer Nomogram
This tool can be used to calculate the risk of bladder cancer recurrence after radical cystectomy

This tool, known as a nomogram, can be used to calculate the risk of bladder cancer recurrence five years after radical cystectomy. It is designed to assess the risk estimate for individual patients -- a key factor in deciding whether adjuvant treatment (for bladder cancer patients this is typically systemic chemotherapy) is likely to be beneficial.

This nomogram, which is based on detailed information drawn from more than 9,000 bladder cancer patients treated by radical cystectomy alone -- the largest study ever -- at 12 centers worldwide, provides a more accurate picture of the five-year risk of recurrence than older assessment tools. The use of this nomogram by patients and their physicians should enable them to evaluate the best treatment plan following surgery. This predictive tool may also be used by researchers to help design and evaluate clinical trials.

Who Is This Tool For?

Supporting Publication
Supporting Publication
Visit PubMed for the journal article that supports this nomogram

This tool can be used by patients and physicians to estimate their risk of experiencing a recurrence of disease after radical cystectomy for localized, locally advanced, or regionally advanced primary invasive bladder cancer. This includes individuals with transitional cell carcinoma (TCC) -- including TCC with elements of squamous cell carcinoma (SCC) or adenocarcinoma, -- SCC, or pure adenocarcinoma of the bladder. This tool is to be used for patients who have had radical cystectomy, including removal of the lymph nodes (pelvic lymphadenectomy), but NOT neoadjuvant or adjuvant chemotherapy or pelvic radiation. They may, however, have received intravesical therapy prior to surgery. This tool may be useful in determining the need for additional therapy after surgery. Patients should use this tool only in consultation with their physicians.

What Information Will You Need?

Needed Information Parameters / Further Explanation
Gender Male or Female
Age Patient's age at the time of radical cystectomy
Number of days from diagnosis to radical cystectomy Must be between 0 and 1,000
Stage According to the 1997 UICC clinical staging system: P0, PA, PIS, P1, P2, P3, P4
Histology Type of bladder cancer diagnosed: transitional cell carcinoma (TCC), squamous cell carcinoma (SCC), or adenocarcinoma (ADENO)
Tumor Grade High or Low

How to Access the Tool

To use the online version of this prediction tool, click here or on "open calculator" in the box at the top of the page. The calculator will open in a pop-up window.

Contact Us

If you have questions or comments, please do not hesitate to contact us at nomograms@mskcc.org.


Last Updated: Mar. 18, 2007
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