Start Year
End Year
Education
Current Position
Civil Servant, Her Majesty’s Civil Service, UK
Publications
Kaushik A, Than T, Petela NJ, Voulgaris M, Percival C, Daniels P, Rafferty JB, Nasmyth KA, Hu B. (2023). Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding. Nat Commun. 14:5929.
Chang JT, Li S, Beckwitt E, Than T, Haluska C, Chandanani J, O’Donnell ME, Zhao X*, Liu S* (*co-corresponding authors). (2022). Smc5/6’s multi-faceted DNA binding capacities stabilize branched DNA structures. Nat Commun 13:7179
Yu Y, Li S, Ser Z, Kuang H, Than T, Guan D, Zhao X, Patel DJ. (2022). Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes. Proc Natl Acad Sci U S A. 119:e2202799119.
Bürmann, F., Lee, B., Than, T., Sinn, L., O’Reilly, F., Yatskevich, S., Rappsilber, J., Hu, B., Nasmyth, K. and Löwe, J. (2019). A folded conformation of MukBEF and cohesin. Nature Structural & Molecular Biology. 26:227-236.